Delaying Menopause: Understanding the Ovary

ABOUT THE EPISODE

In this episode, Dr. Jennifer Garrison, an assistant professor at the Buck Institute for Research on Aging, discusses her work on women’s health and aging. She aims to understand aging mechanisms and develop interventions to promote women’s heath, focusing on the hypothalamus,  and bioactive peptides. Menopause involves changes in ovarian function and chemical signals. Dr. Garrison stresses the need for more research to extend ovarian health. The Center for Reproductive Longevity and Equality supports research on ovarian aging, showing significant progress. The discussion also covers preserving fertility with frozen ovarian tissue and the role of peptides. Emphasis is placed on reframing women’s health and addressing health span inequality between genders.

HERE’S WHAT WE DISCUSS

  • Understanding the underlying mechanisms of aging can lead to interventions that promote women’s health.

  •  The hypothalamus plays a crucial role in regulating various homeostatic systems in the body, including reproductive function.

  •  Bioactive peptides act as chemical signals between the brain and other tissues, influencing various physiological processes.

  •  Menopause is defined as the cessation of menstruation for 12 months, but it also involves changes in ovarian function and the production of chemical signals.

  •  Further research is needed to understand ovarian function and develop interventions to extend ovarian health. The Center for Reproductive Longevity and Equality funds grants to study ovarian aging and has seen significant progress in the field.

  •  Frozen ovarian tissue can be used to preserve fertility in cancer patients.

  •  Peptides play a crucial role in reproductive function, but caution should be exercised when using peptide therapies.

  •  The narrative about women’s health needs to be reframed to focus on maintaining ovarian function for healthy aging.

  •  Women live longer than men on average but spend a longer portion of their lives in poor health, highlighting an inequality in health span.

https://www.buckinstitute.org/lab/garrison-lab/

https://www.linkedin.com/in/drjennifergarrison/

https://gcrle.org/

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